A: If you are talking about absolutes, no. However, you can dramatically reduce the chances of compromise when opening email:
- Use an email provider that pre-scans your mail for malicious content. This is one reason I favor Google. All incoming email is scanned by over a dozen of the leading anti-malware software before it gets to you.
- Install a quality anti-malware software, and keep it updated daily. I’m fond of Bitdefender GravityZone. It will automatically update hourly, and is consistently among the top 3 products in its category.
- Enable application whitelisting. With this active, only applications you have approved can launch/execute/open. Since malware isn’t on your list, it simply cannot launch and cause problems.